Journal of Basic & Clinical Medical Sciences2959-92022959-92102022-09-13241410.58398/0002.000008articleSaima PervaizSara Masood CheemaTahir ShaheenRomeeza TahirZeeshan HaiderSaba ShamimDepartment of Immunology, University of Health Sciences, PakistanThe University of Lahore, PakistanDepartment of Endocrinology and Diabetes, The Children’s Hospital, University of Child Health Sciences, PakistanDepartment of Immunology, University of Health Sciences, PakistanInstitute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, PakistanInstitute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, PakistanThe increasing incidence of allergic diseases requires effective curative strategies for their alleviation. Allergen-specific immunotherapy (AIT) is a causal treatment technique instead of a symptomatic treatment technique for allergies. At present, AIT is being offered utilizing immunization response modifiers (IRMs) or adjuvants. The adjuvant helps in vigorous inaugral as well as long-term IR (immune response), thus enhancing the efficacy of AIT. The successful development of novel additives requires complete knowledge regarding the underdevelopment of novel and conservative additives. Hence, this review describes the applications of nanotechnology in allergic disorders, namely, allergies and asthma. The development of vaccines based on nanoparticles (NPs) is an important strategy for AIT because of their innate physicochemical characteristics, production ease and capacity to incite inherent immunity.